Production of no-carrier-added Lu via the Yb(n,)YbLu process

Hashimoto, Kazuyuki; Matsuoka, Hiromitsu; Uchida, Shoji*

Journal of Radioanalytical and Nuclear Chemistry, 255(3), p.575 - 579, 2003/03

https://doi.org/10.1023/A:1022557121351

The emitter Lu is a promising therapeutic radioisotope for the treatment of cancer. It has a half-life of 6.73 days and maximum energy of 498 keV, resulting in a short range of radiation in tissue. The decay is accompanied by the emission of low energy -radiation with = 208 keV (11.0%) and 113 keV (6.4%) suitable for simultaneous imaging. Lutetium-177 can be usually produced at nuclear reactors with high yield and high specific radioactivity by the Lu(n,)Lu reaction. However, radioisotopes with higher specific radioactivity are required in the field of radioimmunotherapy using labeled monoclonal antibodies. Thus, an alternative production route, namely the Yb(n,)Yb Lu process was studied to produce no-carrier-added (nca) Lu in this work. The radiochemical separation of the nca Lu from the macroscopic ytterbium target was investigated by means of reversed-phase ion-pair HPLC. The nca Lu was obtained in radiochemical pure form with a separation yield of 80%.

Effect of the hydrophobic anion of picrate on the extraction of europium(III) with diamide

Naganawa, Hirochika; Suzuki, Hideya; Tachimori, Shoichi; Nasu, Akinobu*; Sekine, Tatsuya*

Bulletin of the Chemical Society of Japan, 73(3), p.623 - 630, 2000/03

https://doi.org/10.1246/bcsj.73.623

no abstracts in English

Hydration of N,N-bis(2-ethylhexyl)hexanamide in dodecane

; *; Tachimori, Shoichi

Bulletin of the Chemical Society of Japan, 69(10), p.2869 - 2875, 1996/00

https://doi.org/10.1246/bcsj.69.2869

no abstracts in English

Study of hydration and ionization of nitric acid in benzene

; Tachimori, Shoichi

Bulletin of the Chemical Society of Japan, 67, p.2690 - 2699, 1994/00

https://doi.org/10.1246/bcsj.67.2690

no abstracts in English

Negative ions, formation and properties

Shitsuryo Bunseki, 27(4), p.217 - 245, 1979/00

https://doi.org/10.5702/massspec1953.27.217

no abstracts in English

Reaction modeling of ion-pairing extraction of various meatal ions with NTAamide(C6) extractant from hydrochloric acid solution

Kinoshita, Ryoma; Sasaki, Yuji; Kaneko, Masashi; Matsumiya, Masahiko*; Shinoku, Kota*; Shiroishi, Hidenobu*

no journal, , 

Many metal ions are stable in hydrochloric acid solutions as anionic species; diamidic-extractants containing tertiary amino nitrogen atom, such as NTAamide (hexaalkyl-nitrilotriacetamide), are normally protonated in acidic solutions and become cationic extractants. In this study, the ion-pair extraction reactions of metal chloride anions with cationic NTAamide(C6) extractant were investigated. In addition, we attempted to predict the distribution ratio by combining the stability constants of metal chloride complexes and DFT calculations, and compared the results with experimental values.